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Livres
Articles (45)
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Cantilever Sensor for Nanomechanical Detection of Specific Protein Conformations

Mukhopadhyay, Rupa, Sumbayev, Vadim V., Lorentzen, Martin, Kjems, Jørgen, Andreasen, Peter A., Besenbacher, Flemming

Journal:

Nano Letters

Année:

2005

Langue:

english

Fichier:

PDF, 119 KB

english, 2005

Mitochondrial Defunctionalization Supresses Tim-3-Galectin-9 Secretory Pathway in Human Colorectal Cancer Cells and Thus Can Possibly Affect Tumor Immune Escape

Sakhnevych, Svetlana S., Yasinska, Inna M., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.

Journal:

Frontiers in Pharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 1.91 MB

english, 2019

Apoptosis signal-regulating kinase 1 (ASK1) and HIF-1α protein are essential factors for nitric oxide-dependent accumulation of p53 in THP-1 human myeloid macrophages

Mohammad Jawahir, Sally A. Nicholas, Karen Coughlan, Vadim V. Sumbayev

Journal:

Apoptosis

Année:

2008

Langue:

english

Fichier:

PDF, 326 KB

english, 2008

Involvement of hypoxia-inducible factor-1 HiF(1α) in IgE-mediated primary human basophil responses

Vadim V. Sumbayev, Sally A. Nicholas, Claire L. Streatfield, Bernhard F. Gibbs

Journal:

European Journal of Immunology

Année:

2009

Langue:

english

Fichier:

PDF, 313 KB

english, 2009

PI3 kinase and direct S-nitrosation are involved in down-regulation of apoptosis signal-regulating kinase 1 during LPS-induced Toll-like receptor 4 signalling

Vadim V. Sumbayev

Journal:

Immunology Letters

Année:

2008

Langue:

english

Fichier:

PDF, 363 KB

english, 2008

Hypoxia-inducible Factor 1 as one of the “Signaling Drivers” of Toll-like Receptor-Dependent and Allergic Inflammation

Vadim V. Sumbayev, Sally A. Nicholas

Journal:

Archivum Immunologiae et Therapiae Experimentalis

Année:

2010

Langue:

english

Fichier:

PDF, 310 KB

english, 2010

Involvement of xanthine oxidase and hypoxia-inducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1β

Sally A. Nicholas, Vladimir V. Bubnov, Inna M. Yasinska, Vadim V. Sumbayev

Journal:

Cellular and Molecular Life Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 513 KB

english, 2011

The involvement of hypoxia-inducible factor 1 alpha in Toll-like receptor 7/8-mediated inflammatory response

Sumbayev, Vadim V, Nicholas, Sally A

Journal:

Cell Research

Année:

2009

Langue:

english

Fichier:

PDF, 752 KB

english, 2009

The role of redox-dependent mechanisms in the downregulation of ligand-induced Toll-like receptors 7, 8 and 4-mediated HIF-1α prolyl hydroxylation

Nicholas, Sally A, Sumbayev, Vadim V

Journal:

Immunology & Cell Biology

Année:

2009

Langue:

english

Fichier:

PDF, 479 KB

english, 2009

The involvement of sphingosine kinase 1 in LPS-induced Toll-like receptor 4-mediated accumulation of HIF-1α protein, activation of ASK1 and production of the pro-inflammatory cytokine IL-6

Pitson, Stuart M, Waxman, Jonathan, Sumbayev, Vadim V, Pchejetski, Dmitri, Nunes, Joao, Coughlan, Karen, Lall, Harjinder

Journal:

Immunology & Cell Biology

Année:

2010

Langue:

english

Fichier:

PDF, 489 KB

english, 2010

Azinomycin epoxide induces activation of apoptosis signal-regulating kinase 1 (ASK1) and caspase 3 in a HIF-1α-independent manner in human leukaemia myeloid macrophages

Maxwell A. Casely-Hayford, Sally A. Nicholas, Vadim V. Sumbayev

Journal:

European Journal of Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 683 KB

english, 2009

LPS-induced Toll-like receptor 4 signalling triggers cross-talk of apoptosis signal-regulating kinase 1 (ASK1) and HIF-1α protein

Vadim V. Sumbayev

Journal:

FEBS Letters

Année:

2008

Langue:

english

Fichier:

PDF, 700 KB

english, 2008

Myeloid cell death associated with Toll-like receptor 7/8-mediated inflammatory response. Implication of ASK1, HIF-1alpha, IL-1beta and TNF-alpha

Sally A. Nicholas, Abraham E. Oniku, Vadim V. Sumbayev

Journal:

Molecular Immunology

Année:

2010

Langue:

english

Fichier:

PDF, 774 KB

english, 2010

Mesangial cells but not hepatocytes are protected against NO/O2− cogeneration: mechanistic considerations

Vadim V. Sumbayev, Katrin B. Sandau, Bernhard Brüne

Journal:

European Journal of Pharmacology

Année:

2002

Langue:

english

Fichier:

PDF, 279 KB

english, 2002

S-Nitrosation of thioredoxin in the nitrogen monoxide/superoxide system activates apoptosis signal-regulating kinase 1

Inna M Yasinska, Anna V Kozhukhar, Vadim V Sumbayev

Journal:

Archives of Biochemistry and Biophysics

Année:

2004

Langue:

english

Fichier:

PDF, 263 KB

english, 2004

Regulation of MAP kinase-dependent apoptotic pathway: implication of reactive oxygen and nitrogen species

Vadim V. Sumbayev, Inna M. Yasinska

Journal:

Archives of Biochemistry and Biophysics

Année:

2005

Langue:

english

Fichier:

PDF, 449 KB

english, 2005

Dysfunctional mitochondria contain endogenous high-affinity human Toll-like receptor 4 (TLR4) ligands and induce TLR4-mediated inflammatory reactions

Sally A. Nicholas, Karen Coughlan, Inna Yasinska, Gurprit S. Lall, Bernhard F. Gibbs, Luigi Calzolai, Vadim V. Sumbayev

Journal:

The International Journal of Biochemistry & Cell Biology

Année:

2011

Langue:

english

Fichier:

PDF, 966 KB

english, 2011

Nitric oxide inhibits HIF-1α protein accumulation under hypoxic conditions: implication of 2-oxoglutarate and iron

Anna V. Kozhukhar, Inna M. Yasinska, Vadim V. Sumbayev

Journal:

Biochimie

Année:

2006

Langue:

english

Fichier:

PDF, 565 KB

english, 2006

A novel pesticide-induced conformational state of the oestrogen receptor ligand-binding domain, detected by conformation-specific peptide binding

Vadim V. Sumbayev, Eva C. Bonefeld-Jørgensen, Troels Wind, Peter A. Andreasen

Journal:

FEBS Letters

Année:

2005

Langue:

english

Fichier:

PDF, 316 KB

english, 2005

Novel modes of oestrogen receptor agonism and antagonism by hydroxylated and chlorinated biphenyls, revealed by conformation-specific peptide recognition patterns

Vadim V. Sumbayev, Jan K. Jensen, Jacob A. Hansen, Peter A. Andreasen

Journal:

Molecular and Cellular Endocrinology

Année:

2008

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2008

HIF-1α protein is an essential factor for protection of myeloid cells against LPS-induced depletion of ATP and apoptosis that supports Toll-like receptor 4-mediated production of IL-6

Harjinder Lall, Karen Coughlan, Vadim V. Sumbayev

Journal:

Molecular Immunology

Année:

2008

Langue:

english

Fichier:

PDF, 453 KB

english, 2008

S-nitrosylation of thioredoxin mediates activation of apoptosis signal-regulating kinase 1

Vadim V Sumbayev

Journal:

Archives of Biochemistry and Biophysics

Année:

2003

Langue:

english

Fichier:

PDF, 216 KB

english, 2003

HIF-1α protein as a target for S-nitrosation

Vadim V Sumbayev, Andreja Budde, Jie Zhou, Bernhard Brüne

Journal:

FEBS Letters

Année:

2003

Langue:

english

Fichier:

PDF, 248 KB

english, 2003

S-nitrosation of Cys-800 of HIF-1α protein activates its interaction with p300 and stimulates its transcriptional activity

Inna M Yasinska, Vadim V Sumbayev

Journal:

FEBS Letters

Année:

2003

Langue:

english

Fichier:

PDF, 203 KB

english, 2003

Differential control of hypoxia-inducible factor 1 activity during pro-inflammatory reactions of human haematopoietic cells of myeloid lineage

Gibbs, Bernhard F., Yasinska, Inna M., Pchejetski, Dmitri, Wyszynski, Rafal W., Sumbayev, Vadim V.

Journal:

The International Journal of Biochemistry & Cell Biology

Année:

2012

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2012

Microscopic Analysis of the Interaction of Gold Nanoparticles with Cells of the Innate Immune System

García, César Pascual, Sumbayev, Vadim, Gilliland, Douglas, Yasinska, Inna M., Gibbs, Bernhard F., Mehn, Dora, Calzolai, Luigi, Rossi, François

Journal:

Scientific Reports

Année:

2013

Langue:

english

Fichier:

PDF, 918 KB

english, 2013

An Electrochemical Sensor Based on the Human Estrogen Receptor Ligand Binding Domain

Hansen, Jacob A., Sumbayev, Vadim V., Gothelf, Kurt V.

Journal:

Nano Letters

Année:

2007

Langue:

english

Fichier:

PDF, 115 KB

english, 2007

Interleukin-1 beta induces the expression and production of stem cell factor by epithelial cells: crucial involvement of the PI-3K/mTOR pathway and HIF-1 transcription complex

Wyszynski, Rafal W, Gibbs, Bernhard F, Varani, Luca, Iannotta, Daniela, Sumbayev, Vadim V

Journal:

Cellular & Molecular Immunology

Année:

2014

Langue:

english

Fichier:

PDF, 2.37 MB

english, 2014

Peroxynitrite as an alternative donor of oxygen in HIF-1α proline hydroxylation under low oxygen availability

Sumbayev, Vadim V., Yasinska, Inna M.

Journal:

Free Radical Research

Année:

2006

Langue:

english

Fichier:

PDF, 200 KB

english, 2006

Gold Nanoparticles Downregulate Interleukin-1β-Induced Pro-Inflammatory Responses

Sumbayev, Vadim V., Yasinska, Inna M., Garcia, Cesar Pascual, Gilliland, Douglas, Lall, Gurprit S., Gibbs, Bernhard F., Bonsall, David R., Varani, Luca, Rossi, François, Calzolai, Luigi

Journal:

Small

Année:

2013

Langue:

english

Fichier:

PDF, 637 KB

english, 2013

The immune receptor Tim-3 mediates activation of PI3 kinase/mTOR and HIF-1 pathways in human myeloid leukaemia cells

Prokhorov, Alexandr, Gibbs, Bernhard F., Bardelli, Marco, Rüegg, Laura, Fasler-Kan, Elizaveta, Varani, Luca, Sumbayev, Vadim V.

Journal:

The International Journal of Biochemistry & Cell Biology

Année:

2015

Langue:

english

Fichier:

PDF, 2.33 MB

english, 2015

[Methods in Enzymology] Nitric Oxide, Part F Volume 440 || Protein S‐Nitrosation in Signal Transduction: Assays for Specific Qualitative and Quantitative Analysis

Sumbayev, Vadim V.

Année:

2008

Langue:

english

Fichier:

PDF, 152 KB

english, 2008

Highly Specific Targeting of Human Leukocytes Using Gold Nanoparticle-Based Biologically Active Conjugates

Gibbs, Bernhard F., Yasinska, Inna M., Calzolai, Luigi, Gilliland, Douglas, Sumbayev, Vadim V.

Journal:

Journal of Biomedical Nanotechnology

Année:

2014

Langue:

english

Fichier:

PDF, 8.39 MB

english, 2014

The role of basophils in allergic inflammation

Raap, Ulrike, Sumbayev, Vadim V., Gibbs, Bernhard F.

Journal:

Allergo Journal

Année:

2015

Langue:

english

Fichier:

PDF, 365 KB

english, 2015

The role of basophils in allergic inflammation

Raap, Ulrike, Sumbayev, Vadim V., Gibbs, Bernhard F.

Journal:

Allergo Journal International

Année:

2015

Langue:

english

Fichier:

PDF, 366 KB

english, 2015

129 Involvement of the Hypoxia-Inducible Factor-1 Transcription Complex in the Inflammatory Responses of Human Mast Cells and Basophils

Yasinska, Inna, Sumbayev, Vadim, Gibbs, Bernhard

Journal:

World Allergy Organization Journal

Année:

2012

Langue:

english

Fichier:

PDF, 82 KB

english, 2012

61 Hypoxia-Inducible Factor 1 (HIF-1) Transcription is a “Signalling Driver” for Allergic Inflammation, Host Innate Immune Defence and Leukaemia Progression

Sumbayev, Vadim, Yasinska, Inna, Gibbs, Bernhard

Journal:

World Allergy Organization Journal

Année:

2012

Langue:

english

Fichier:

PDF, 99 KB

english, 2012

The immune receptor Tim-3 acts as a trafficker in a Tim-3/galectin-9 autocrine loop in human myeloid leukemia cells

Gonçalves Silva, Isabel, Rüegg, Laura, Gibbs, Bernhard F., Bardelli, Marco, Fruewirth, Alexander, Varani, Luca, Berger, Steffen M., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.

Journal:

OncoImmunology

Année:

2016

Langue:

english

Fichier:

PDF, 2.14 MB

english, 2016

Crucial involvement of xanthine oxidase in the intracellular signalling networks associated with human myeloid cell function

Abooali, Maryam, Lall, Gurprit S., Coughlan, Karen, Lall, Harjinder S., Gibbs, Bernhard F., Sumbayev, Vadim V.

Journal:

Scientific Reports

Année:

2014

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2014

Differential Role of Hypoxia-Inducible Factor 1 Alpha in Toll-Like Receptor-Mediated and Allergic Inflammatory Reactions

Vadim V. Sumbayev PhD,Sally A. Nicholas PhD…

Journal:

World Allergy Organization Journal

Année:

2010

Langue:

english

Fichier:

PDF, 325 KB

english, 2010

Biochemical mechanisms implemented by human acute myeloid leukemia cells to suppress host immune surveillance

Yasinska, Inna M., Gonçalves Silva, Isabel, Sakhnevych, Svetlana, Gibbs, Bernhard F., Raap, Ulrike, Fasler-Kan, Elizaveta, Sumbayev, Vadim V.

Journal:

Cellular & Molecular Immunology

Année:

2018

Langue:

english

Fichier:

PDF, 483 KB

english, 2018

Effects of Stem Cell Factor on Hypoxia-Inducible Factor 1 Alpha Accumulation in Human Acute Myeloid Leukaemia and LAD2 Mast Cells

Gibbs, Bernhard F., Yasinska, Inna M., Oniku, Abraham E., Sumbayev, Vadim V., Sozzani, Silvano

Journal:

PLoS ONE

Année:

2011

Langue:

english

Fichier:

PDF, 560 KB

english, 2011

Expression of functional neuronal receptor latrophilin 1 in human acute myeloid leukaemia cells

Sumbayev, Vadim V., Silva, Isabel Gonçalves, Blackburn, Jennifer, Gibbs, Bernhard F., Yasinska, Inna M., Garrett, Michelle D., Tonevitsky, Alexander G., Ushkaryov, Yuri A.

Journal:

Oncotarget

Année:

2016

Langue:

english

Fichier:

PDF, 6.49 MB

english, 2016

Expression of functional neuronal receptor latrophilin 1 in human acute myeloid leukaemia cells

Sumbayev, Vadim V., Silva, Isabel Gonçalves, Blackburn, Jennifer, Gibbs, Bernhard F., Yasinska, Inna M., Garrett, Michelle D., Tonevitsky, Alexander G., Ushkaryov, Yuri A.

Journal:

Oncotarget

Année:

2016

Fichier:

PDF, 6.49 MB

2016

Editorial: The Challenge of New Therapeutic Approaches for Unmet Therapeutic Needs

Rosa, Arianna Carolina, Mio, Mitsunobu, Andreadou, Ioanna, Sumbayev, Vadim V.

Journal:

Frontiers in Pharmacology

Année:

2020

Fichier:

PDF, 218 KB

2020